Filgrastim, filgrastim-sndz, and tbo-filgrastim may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- redness, swelling, bruising, itching or a lump in the place where the medication was injected
- bone, joint, or muscle pain
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
- pain in the left upper part of the stomach or the tip of the left shoulder
- shortness of breath
- trouble breathing
- fast breathing
- swelling around the mouth, face, eyes, stomach, feet, ankles, or lower legs
- unusual bruising or purple markings under the skin
- unusual bleeding or bruising
- decreased urination
Some people who used filgrastim or filgrastim-sndz to treat severe chronic neutropenia developed leukemia (cancer that starts in the bone marrow) or changes in the bone marrow cells that show that leukemia may develop in the future. People who have severe chronic neutropenia may develop leukemia even if they do not use filgrastim. There is not enough information to tell if filgrastim or filgrastim-sndz increases the chance that people with severe chronic neutropenia will develop leukemia. Talk to your doctor about the risks of using this medication.
Filgrastim, filgrastim-sndz, and tbo-filgrastim may cause other side effects. Call your doctor if you have any unusual problems while using this medication.