Before taking rifampin,
tell your doctor and pharmacist if you are allergic to rifampin, rifabutin (Mycobutin), rifapentine (Priftin), any other medications, or any of the ingredients in rifampin capsules. Ask your doctor or pharmacist for a list of the ingredients.
tell your doctor if you are taking any of the following medications: atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), saquinavir (Invirase), tipranavir (Aptivus), or ritonavir (Norvir) and saquinavir (Invirase) taken together. Your doctor will probably tell you not to take rifampin if you are taking any of these medications.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); antifungals such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox), and ketoconazole (Nizoral); atovaquone (Mepron, in Malarone); barbiturates such as phenobarbital; beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); calcium channel blockers such as diltiazem (Cardizem, Tiazac, Dilacor), nifedipine (Adalat, Procardia), and verapamil (Calan, Covera, Isoptin, Verelan); chloramphenicol; clarithromycin (Biaxin); cyclosporine (Gengraf, Neoral, Sandimmune); dapsone; diazepam (Valium); doxycycline (Doryx, Monodox, Vibramycin); enalapril (Vaseretic); fluoroquinolone antibiotics such as ciprofloxacin (Cipro); gemfibrozil (Lopid); haloperidol (Haldol); isoniazid (in Rifater, Rifamate); levothyroxine (Levoxyl, Synthroid); medications for irregular heartbeat such as digoxin (Lanoxin), disopyramide (Norpace), mexiletine, and quinidine; medications for seizures such as phenytoin (Dilantin); methadone (Dolophine, Methadose); narcotic medications for pain; oral medications for diabetes; probenecid (Probalan); quinine (Qualquin); steroids such as dexamethasone (Decadron), methylprednisolone (Medrol), and prednisone; sulfasalazine (Azulfidine); trimethoprim and sulfamethoxazole (Bactrim, Septra); tacrolimus; (Prograf); theophylline (Theochron, Theolair); tricyclic antidepressants such as amitriptyline (in Limbitrol) and nortriptyline (Pamelor); and zidovudine (Retrovir, in Trizivir). Many other medications may interact with rifampin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
if you are taking antacids, take rifampin at least 1 hour before you take the antacids..
tell your doctor if you are taking or using hormonal contraceptives (birth control pills, patches, rings, implants, and injections). Rifampin can decrease the effectiveness of hormonal contraceptives. You should use another method of birth control while taking this medication. Talk to your doctor about birth control while taking rifampin.
tell your doctor if you have or have ever had diabetes, porphyria (condition in which certain natural substances build up in the body and may cause stomach pain, changes in thinking and behavior, or other symptoms), any condition that affects your adrenal gland (small gland next to the kidney that produces important natural substances) or liver disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking rifampin, call your doctor.
tell your doctor if you wear soft contact lenses. Rifampin may cause permanent red stains on your contact lenses.