Before taking lansoprazole, clarithromycin, and amoxicillin,
tell your doctor and pharmacist if you are allergic to any antibiotics azithromycin (Zithromax, Zmax), clarithromycin (Biaxin), erythromycin (E.E.S. 400, others), cephalosporins such as cefaclor, cefadroxil, cefuroxime (Ceftin, Zinacef), and cephalexin (Keflex); other beta-lactam antibiotics such as penicillin or amoxicillin (Amoxil, Moxatag); lansoprazole (Prevacid); any other medications; or any of the ingredients in amoxicillin tablets, clarithromycin capsules, or lansoprazole capsules. Ask your pharmacist for a list of the ingredients.
tell your doctor if you are taking any of the following medications: astemizole (Hismanal) (not available in the U.S.), cisapride (Propulsid) (not available in the U.S.), colchicine (Colcyrs, Mitigare), dihydroergotamine (D.H.E, Migranal), ergotamine (Ergomar, in Cafergot, in Migergot), lovastatin (Advicor, Altoprev), pimozide (Orap), quetiapine (Seroquel), rilpivirine (Edurant), simvastatin (Zocor, in Simcor, in Vytorin), or terfenadine (Seldane) (not available in the U.S.). Your doctor will probably tell you not to take lansoprazole, clarithromycin, and amoxicillin if you are taking one or more of these medications.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Nexterone, Pacerone); other antibiotics such as ampicillin; anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); certain antifungal medications including itraconazole (Onmel, Sporanox), ketoconazole, and voriconazole (Vfend); certain benzodiazepines including alprazolam (Niravam, Xanax), midazolam, and triazolam (Halcion); bromocriptine (Cycloset, Parlodel); certain calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor), nifedipine (Adalat, Procardia), and verapamil (Calan, Verelan, others); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); certain cholesterol-lowering medications including atorvastatin (Lipitor) and pravastatin (Pravachol); cilostazol (Pletal); cyclosporine (Gengraf, Neoral, Sandimmune); dasatinib (Sprycel); digoxin (Lanoxin); disopyramide (Norpace); dofetilide (Tikosyn); erlotinib (Tarceva); certain medications for HIV such as atazanavir Reyataz), didanosine (Videx), efavirenz (Sustiva), etravirine (Intelence), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, in Kaletra), saquinavir (Invirase), and zidovudine (Retrovir, in Trizivir, in Combivir); insulin; iron supplements; maraviroc (Selzentry); methylprednisolone (Medrol); methotrexate (Otrexup, Rasuvo, Xatmep); mycophenolate (Cellcept); nateglinide (Starlix); nilotinib (Tasigna); phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos); probenecid (Probalan, in Col-probenecid); procainamide; quinidine (in Nuedexta); repaglinide (Prandin); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); rifapentine (Priftin); rosiglitazone (Avandia); sildenafil (Revatio, Viagra); sotalol (Betapace, Sorine); tacrolimus (Astagraf XL, Prograf); tadalafil (Adcirca, Cialis); theophylline (Theo 24, Theochron, Uniphyl, others); tolterodine (Detrol); valproate (Depacon); vardenafil (Levitra, Staxyn); and vinblastine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with lansoprazole, clarithromycin, and amoxicillin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
if you are taking sucralfate (Carafate), take it 30 minutes after you take lansoprazole, clarithromycin, and amoxicillin.
tell your doctor what herbal products you are taking, especially St. John's wort.
tell your doctor if you have or have ever had a QT prolongation (an irregular heart rhythm that can lead to fainting, loss of consciousness, seizures, or sudden death) or an irregular heartbeat; low levels of potassium or magnesium in your blood; asthma, allergies, hives, hay fever, myasthenia gravis (a disease that causes muscle weakness); or kidney or liver disease.
tell your doctor if you are pregnant, plan to become pregnant or are breastfeeding. If you become pregnant while taking these medications, call your doctor.
if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking lansoprazole, clarithromycin, and amoxicillin.