Risperdal Consta (Risperidone)
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(ris per' i done)
Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take or use antipsychotics (medications for mental illness) such as risperidone have an increased risk of death during treatment.
Talk to your doctor about the risks of receiving risperidone extended-release injection.
Risperidone extended-release (long-acting) injection is used to treat schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Risperidone extended-release injection is used alone or in combination with lithium (Lithobid) or valproate (Depacon) to treat people who have bipolar I disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of severe mania, and other abnormal moods). Risperidone is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.
Risperidone extended-release injection comes as a solution to be injected into a muscle by a healthcare provider. Risperidone extended-release injection is usually given once every 2 weeks. Your doctor will prescribe a similar medication to take by mouth for 3 weeks until risperidone extended-release injection is fully working.
Risperidone extended-release injection may help control your symptoms but will not cure your condition. Continue to keep appointments to receive risperidone injection even if you feel well. Talk to your doctor if you do not feel like you are getting better during your treatment with risperidone injection.
Before receiving risperidone extended-release injection,
- tell your doctor and pharmacist if you are allergic to risperidone, any other medications, or any of the ingredients in risperidone extended-release injection. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants such as fluoxetine (Prozac, Sarafem, Selfemra) and paroxetine (Brisdelle, Paxil, Pexeva); cimetidine; clozapine (Clozaril, Fazaclo ODT, Versacloz); dopamine agonists such as bromocriptine (Cycloset, Parlodel), cabergoline, levodopa and carbidopa (Sinemet), and ropinirole (Requip); medications for anxiety, blood pressure, or mental illness; medications for seizures such as carbamazepine (Carbatrol, Epitol, Equetro, Teril, others) phenobarbital, and phenytoin (Dilantin, Phenytek); ranitidine (Zantac); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have a low number of white blood cells or if any other medication has ever caused a decrease in your white blood cells. Also tell your doctor if you have had or have ever had a stroke, a ministroke, a heart attack, heart failure, irregular heartbeat, dyslipidemia (high cholesterol levels), seizures, difficulty swallowing, trouble keeping your balance, Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance), or heart, kidney or liver disease. Tell your doctor if you or anyone in your family has or has ever had diabetes and if you have severe vomiting, diarrhea or signs of dehydration now, or if you develop these symptoms at any time during your treatment. Also, tell your doctor if you have or have had thoughts about harming or killing yourself.
- tell your doctor if you are pregnant, or if you plan to become pregnant. If you become pregnant during your treatment or for up to 12 weeks after your final injection with risperidone extended-release injection, call your doctor.
- do not breastfeed while receiving risperidone extended-release injection and for at least 12 weeks after your final injection.
- you should know that receiving risperidone extended-release injection may make you drowsy and may affect your ability to think clearly, make decisions, and react quickly. Do not drive a car or operate machinery during your treatment with risperidone injection until you know how this medication affects you.
- you should know that alcohol can add to the drowsiness caused by this medication. Do not drink alcohol during your treatment with risperidone extended-release injection.
- you should know that you may experience hyperglycemia (increases in your blood sugar) while you are receiving this medication, even if you do not already have diabetes. If you have schizophrenia, you are more likely to develop diabetes than people who do not have schizophrenia, and receiving risperidone extended-release injection or similar medications may increase this risk. Tell your doctor immediately if you have any of the following symptoms during your treatment: extreme thirst, frequent urination, extreme hunger, blurred vision, or weakness. It is very important to call your doctor as soon as you have any of these symptoms, because high blood sugar can cause a serious condition called ketoacidosis. Ketoacidosis may become life-threatening if it is not treated at an early stage. Symptoms of ketoacidosis include dry mouth, nausea and vomiting, shortness of breath, breath that smells fruity, and decreased consciousness.
- you should know that risperidone extended-release injection may cause dizziness, lightheadedness, fast or slow heartbeat, and fainting when you get up too quickly from a lying position, especially right after you receive your injection. If you feel dizzy or drowsy after you receive your injection, you will need to lie down until you feel better. During your treatment, you should get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
- you should know that risperidone extended-release injection may make it harder for your body to cool down when it gets very hot or warm up when it gets very cold. Tell your doctor if you plan to do vigorous exercise or be exposed to extremely high or low temperatures.
Unless your doctor tells you otherwise, continue your normal diet.
Risperidone injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- weight change (gain or loss)
- blurred vision
- dry mouth
- dry skin
- increased saliva
- breast enlargement or discharge
- late or missed menstrual periods
- decreased sexual ability
- dizziness, feeling unsteady, or having trouble keeping your balance
Some side effects can be serious. If you experience any of these symptoms or those listed in the SPECIAL PRECAUTIONS section, call your doctor immediately or get emergency medical treatment:
- muscle stiffness
- difficulty swallowing or breathing
- fast or irregular pulse
- unusual movements of your face or body that you cannot control
- slow movements or shuffling walk
- painful erection of the penis that lasts for hours
Risperidone extended-release injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to risperidone extended-release injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.